The first appearance of John Truman Carter, Sr. portrayed by George Plimpton.
The title is from the common expression: I am not my brother's keeper.
Julianna Margulies (Carol Hathaway) & Eric Saiet (Alex Dibble) also worked together on episode 1.2, Stripped (2009), of The Good Wife (2009) as Alicia Florrick & Dr. Girtzman respectively.