Death explains to Peter about how bad it would be if Hitler was still alive. There is a small skit with Hitler having his own talk show, in which Hitler announces the phone number of the show: "213 - Du Werdest Eine Krankenschwester Brauchen". Roughly translated that means "213 - You Will Need A Nurse!"
When the doctor tells Peter that he has a fatty corpuscle, Peter asks how it can be a "dead comedian from the silent movie era". The person Peter's referring to is Roscoe 'Fatty' Arbuckle.
This is the only time where Death is voiced by Norm MacDonald. In all subsequent appearances, Death is voiced by Adam Carolla.
Stewie's e-mail address is loismustdie@yahoo.com
Lacey Chabert voiced Meg due to the fact this episode was filmed for season 1 but did not air until season 2.