- Dr. Meredith Grey: We can't help ourselves, we see a line we want to cross it. Maybe it's the thrill of trading the familiar for the unfamiliar, a sort of personal dare, only problem is, once you have crossed it's almost impossible to go back. But if you do manage to make it back across that line, you find safety in numbers.
- Cheyenne Wood: [about the baby she has just given up for adoption] Can I name her?
- Dr. Isobel 'Izzie' Stevens: You can name her for you.
- Dr. Isobel "Izzie" Stevens: She can have more than a trailer park and a graveyard shift at a truck-stop diner. Don't you want that for her? I mean, if you can get past the fact that I'm superior, and that I'm judging you, and telling you what's best for your family... if you can just get past all of that, isn't it possible that I'm also right?
- Nurse Olivia Harper: [shouting on the picket line] Change your own bedpans, Stevens!
- Dr. Isobel "Izzie" Stevens: Yeah, enjoy your syphilis, Olivia.
- Dr. George O'Malley: [striking with the nurses] Sorry, can't help you! Fair hours! Fair wages! Fair hours! Fair... no offense.
- Dr. Meredith Grey: In surgery there is a red line on the floor that marks the point where the hospital goes from being accessible to being off limits to all but a special few. Crossing the line unauthorized is not tolerated. In general, lines are there for a reason, for safety, for security, for clarity. If you choose to cross the line, you pretty much choose to do so at your own risk. So why is it that the bigger the line, the greater the temptation to cross it?
- Dr. Isobel "Izzie" Stevens: George is cowering behind the picket line like a little girl.
- Dr. Sydney Heron: Standing up for what he believes in, that's my kind of little girl! Am I right?
- Dr. Isobel "Izzie" Stevens: [about her daughter she gave for adoption] I wanted better for her than I could do at sixteen.
- Dr. Sydney Heron: [In surgery] Anyone care to probe the wound?
- Dr. Alex Karev, Dr. Cristina Yang: [In unison] I do.
- Dr. Alex Karev: I'd really like to try your method of "healing with love."
- Dr. Sydney Heron: I like the way you think, Alex. You do the honors.