Beginning with season 2, the ABC network's website started running a segment which explained the science behind the patients' cases. For example, it explains in detail why in the episode "Into You Like A Train", the patients that had a pole running through them could not be easily separated, and exactly what their injuries were in layman's terms.
The episode was nominated for Outstanding Writing for Drama Series at the 58th Primetime Emmy Awards along with other Grey's Anatomy episode ''It's the End of the World&As We Know It''
Derek, who is known as McDreamy, is mistakenly referred to as McSteamy, a nickname later given to his former best friend, Mark Sloan.
Every episode of the show is named after a famous song. "Into You Like a Train" is a song by The Psychedelic Furs.