Spike teaches Rocco Bonnaro about fighting, he tells Bonnaro that in a fight he must be "flexible like water, be like water", a very famous quote by Bruce Lee.
The hijackers that Spike and Faye capture on the ship landing on Venus are named Huey, Dewey and Louie are Donald Duck's nephews in the Donald Duck cartoons by Walt Disney. You can see this when Spike is collecting the reward for them at the space port.
Some places in this episode are heavily inspired by the touristic places in Istanbul, Turkey. While the place where Roco was running away from the gang is very similar to Grand Bazaar, the final fight venue is the Sultanahmet Mosque.