Lorne Greene and Richard Hatch earlier co-starred on Battlestar Galactica.
Jim Knaub, a real-life paraplegic, was also a guest star on Lorne Greene's series Code Red the year prior.
At the beginning the crew talks about how they first met six years ago. Assuming that each season equals one year of real time, and this is the sixth season, that might imply they were newly introduced to each other when the show started. However, the show had been on for five years at that time, which would imply they met a year before the show started.
At one point during the various bickering among the crew, Isaac says to Doc, "Well Excuuussse Me." This is a direct reference to Steve Martin, who used that as his catchphrase when he first achieved fame as a stand up comedian.
Unlike most shows that reminisces about past episodes, this was not a compilation of clips of prior episodes.