Espionage at Atlanta's Biological Research Institute (BRI) sets the stage for the penultimate episode of the "MSW" series as a team of experts scrutinizes an international plot to purchase "Project 14," a biological killer virus.
Raul Jaffa (Erick Avari) offers Doctor James Lamont (Time Winters) $two million in exchange for a vial of Project 14, which he developed at BRI, under the threat of retaliation to Doctor Lamont's family if he does not comply with the demand.
BRI Director Mark Reisner (Gregg Henry) assembles a team of federal agents to track Raul Jaffa and Doctor Lamont with advanced technological surveillance equipment.
National Security Agent Nathan Mitchell (Tony Todd), FBI Agent Ed Crider (William O'Leary), and CIA Agent Dennis Quinlan (Peter Van Norden) utilize their departmental resources to assist in the investigation, while enemy agent Carl Van Ness (Gustav Vintas) uses his country's high tech apparatus regiment to counter-spy.
Mark's wife, Karen Reisner (Mary Elizabeth McGlynn), meanwhile, enters a contest to submit a short story for Amateur Mystery Writers' Conference, held in Atlanta this week, at which her dear old friend Jessica Fletcher (Angela Lansbury) is scheduled to deliver an address.
Karen and Mark welcome Jessica to the fashionable Gambier Hotel, which hosts the conference, but when a contest entry becomes switched for an envelope containing a warning with photographs of one to beware, Jessica attempts to correct the mix-up and stumbles across the first body in the victim's hotel room.
Lieutenant Paul Bragg (Gregory Alan Williams) arrives to investigate the murder, as do Mark Reisner, NSA Agent Nathan Mitchell, FBI Agent Ed Crider and CIA Agent Dennis Quinlan, as the remainder of the team views the closed-circuit proceedings, and as several agents warn Karen and Jessica to flee Atlanta, which Jessica refuses to do, or at least until after she delivers her speech.
After more cloak and dagger activity, Jessica witnesses the second murder at Gambier Hotel, after someone has slipped into her jacket pocket a the key to a locker, which, after unopened, turns an audio-cassette tape and the message, "Mrs. Parker's Revenge."
Jessica understands the implication of the correlation between Project 14 and "Mrs. Parker's Revenge" and, thereby, sets the plans into motion to trap the killer of the second victim, while risking the lives of an estimated two million citizens in the process.
(Note: this episode title is not related to the character of Mrs. Parker in episode "Something Borrowed, Someone Blue (#5.09).")
The cast is rounded out by Gena Acosta as Detective, Karen Hensel as Techie, and Frederick Dawson as Hotel Clerk.
This episode represents the only acting credit to date for Gena Acosta, as well as the second of two "MSW" performances each for Gustav Vintas, William O'Leary and Time Winters, the third of three each for Karen Hensel and Peter Van Norden, and the seventh of seven "MSW's" (six characters) for Gregg Henry.
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