***SPOILERS*** The NYPD are on the lookout for a pair of blue blood or pure bread bloodhound who escaped from a van that was involved in a car accident. With NYPD police detectives James Hollaran & Frank Arcaro, James Franciscus & Harry Bellaver, on the case they track down the two lost mutts in midtown Manhattan sniffing for their next meal. As we soon find out the two dogs were hired, from their master in far off Colorado, to track down this missing 5 year old girl Lynn Whitmore, Janice Manzo, who disappeared from her 5th Av penthouse apartment.
Det. Arcaro knowing a thing or two about bloodhounds, a friend of his raised them in upstate New York, soon realizes what the bloodhounds were here in the city for. That's when through the dogs keeper, who was injured in the car crash, told them that he was supposed to find the Whitmore's Charles & Jane, Byron Sanders & Phyllis Hill, missing daughter Lynn. Going against his bosses Let. Mike Parker's, Horace Mcmahon, orders both defectives Arcaro & Halloran let the dogs loose and with only the scent of Lynn's rag doll they eventually tracked the little girl down in the wilds of New York's Central Park thus accomplishing in less then two hours what the entire 30,000 members of the NYPD couldn't do in six since they were put on the case.
What the two bloodhounds accomplished so impressed Let. Mike Parker who at first wanted to have nothing to do with the mutts that by the time the "Naked City" episode ended he suggested to his boss the NYC Police Commissioner to have a bloodhound assigned to every police prescient in the entire city! That in him realizing that the nose of a bloodhound is far more effective in finding missing persons than all the members of the police missing person department combined!