The House to which Brooke takes Lucas when they are making out in the hot tub is the same house lived in by Haley, Nathan and Jamie in Seasons 5 and 6.
The episode is named after a song by Mike & the Mechanics.
The CD that Peyton gives Brooke to help Brooke's connection to Lucas is the Scottish band Travis "12 Memories". Track 8 is Love Will Come Through. Track 11 is Walking Down the Hill. Travis's track Re-Offender, which features being betrayed by a loved one, features heavily in future One Tree Hill episodes.