First appearance of Lenny and Helen Lovejoy.
The restaurant that Jacques and Marge attend is called "Shorty's"; it was originally intended that a chef's hat would be shown moving around in the background, implying that the owner was short, but the concept was dropped as it seemed to be too much of a silly idea.
The credits are short (no chalkboard or couch gag) because, according to the DVD commentary, the episode ran long due to Albert Brooks' ad-libs.
Before it was retitled "Life on the Fast Lane" this episode was called "Jacques to be Wild". Although this title doesn't seem to make any sense, it was a revised title based on the very first iteration of the story. In the original story, Marge didn't take bowling lessons; she took tennis lessons from a handsome tennis pro named Bjorn. Of course, the original title was "Bjorn to be Wild".