Joseph Schildkraut's second wife (of 29 years) died while he was filming this episode. Coming from a theatrical family, he insisted on finishing the production before he'd begin mourning. Here, he plays an elderly man who must choose between a new body for himself or living the rest of his life with his wife in a pain-wracked body.
In this episode, John Holt (Joseph Schildkraut) is 79 years of age, and his wife Marie Holt (Alma Platt) is five years his junior, at 74 years of age. In real life, John Schildkraut was 66 years of age and Alma Platt was five years his senior, at 71 years of age. The episode focuses on age and becoming young again; in 1962, the year this episode originally aired, the average life expectancy of a male was 66.90 years and 73.50 years for a female.
Rod Serling's opening narration contains the words "Twilight Zone", which is usual; however, there is an unusual aspect here, as these two words do not occur consecutively within it.
The price of $5,000 seems rather low if it is 60's dollars (about $50,000 in 2024) for a new life and would be almost laughable if it was currency from the 21st or later centuries unless they were in fact some sort of "New" Dollar that had been introduced in the future that was much more valuable.