Thousands of live bees were used during production, with the understanding that the bees would not sting without a queen present. However, this theory proved incorrect, and Vanessa Morley, who played the Samantha Mulder clones, was stung during filming. She kept quiet and did not react until the scene had finished filming, leading Frank Spotnitz to call her "a trooper". The crew even did a ceremony for her, and Gillian Anderson gave her a trophy because of being so brave.
The title "Herrenvolk" is a German word which was popular in Nazi Germany as it means "master race".
This is the first episode not to be shot by John S. Bartley, who had moved on to new pastures. The director of photography was Ron Stannett, who was fired midway through the shoot because the producers didn't care for the way he was filming the episode. During this traumatic time, Chris Carter's services were very much needed, but he was in the midst of prepping "Millennium (1996)."
First appearance of Marita Covarrubias.
First introduction of bees in the series, which will play an important role in the ongoing X-files mythology.