In the scene where Izzy swallows the key, Danny Bonaduce really did swallow an actual key to the surprise of the crew.
First appearance of Kay Panabaker as Lindsey Willows.
This is the first episode showing the miniatures of the crime scenes.
In the United Kingdom, sometimes this episode and the previous episode are stitched together to create a feature-length presentation called "The CSI Movie: Built to Kill".