When Discord's apples were running through Ponyville, in the background Lyra and Bon Bon were proposing to each other.
Final speaking role for the Cutie Mark Crusaders and Sugar Belle.
Friendship Report: Big Mac and Sugar Belle learned they don't have to go out and make a grand gesture and just be simple.
Not only is this the last episode where neither Apple Jack nor Fluttershy had a single line of dialogue, but is also the last episode where any of the main characters doesn't have any lines of dialogue. Spike's the only main character to appear and speak in this episode.
Not only is this the last episode where Twilight Sparkle, Rarity, Pinkie Pie and Rainbow Dash are absence, but these are also the last absences in the series as a whole.