When Betty's family goes to Guadalajara, Betty's nephew, Justin, is in rehearsal as Tony's understudy in the school musical "West Side Story". One of the family members he meets is their "Aunt Mirta" being played by Rita Moreno who won an Oscar in 1960 for playing "Anita" in the film version of "West Side Story".
Justina Machado and Rita Moreno play mother-in-law and daughter-in-law in this episode. They would later go on to play mother and daughter in One Day at a Time (2017).
Alexis' ex-girlfriend is a model named Jordan Dunn. Jourdan Dunn is a real model, from the UK, who was discovered in 2006, the same year in the show first aired.