Characters repeatedly speak of infection and it's spread. Whilst they would have grasped that disease transferred from person to person in the 16thC, the knowledge of germs and infection wouldn't come about until nearly 400 years later. People likely would have spoken of pestilence or scourge, but infection most certainly wouldn't have been in their vocabulary or understanding.
Filmed just before or right at the beginning of the real life Covid-19 Pandemic.