Some of the kids from the books are cut out completely, including Allison, Benjamin, Calvin, D.J., Dameon, Deedee, Jason, Joy, Kathy, Mac, Paul, Ron, and Terrance. There's also a student in the show who wasn't in the book: Elizabeth.
Maurecia's hair is colored purple; it was colored pink in the Wayside film.
All the voice actors reprise from Wayside: The Movie except for Michael Cera. Todd is voiced by Mark Rendall.
The series stopped airing on American television networks in 2013; all the episodes were officially restored on YouTube a few years later.