When the FBI arrests Zane Donovan before bringing him to Eureka, a box for Half Life 2 can be seen. The Half Life series is originally about a top secret research facility called Black Mesa, not unlike Global Dynamics
First appearance of Niall Matter as Zane Donovan.
In the episode, Jack doesn't know a few terms despite being unaffected. While CDC does indeed stand for Centers for Disease Control (and Prevention) he says that NIH stands for National something health. NIH stands for National Institutes of Health. Later on, Allison asks what a mangabee is and Jack doesn't know. It's a species of monkey, which is why the veterinarian mentions them