When at the restaurant while everyone is waiting for Peter's order, Brian appears and disappears multiple times.
There is a change in Babs Pewterschmitts backstory. Earlier in the series it is established that she is a holocaust survivor, this time she states that she grew up in a small Rhode Island town.
When Stewie brags to Brian about an award he won, Brian tells Stewie that it's only a participation award and is meaningless like the rest of his awards (supposedly all being participation awards). Yet earlier in the series, Stewie wins an actual award for having the best pig in the competition at Quahog Clam Fest.