"El Pato" is Spanish for "Duck." The name is a play on the famous "El Niño" storm system.
In a callback to Scrooge's as yet unexplained enmity towards Santa Claus, the mansion has a booby trap clearly marked "Santa Trap".
Launchpad's attempt to describe time as not being in a straight line resembles the Tenth Doctor's attempt to explain time as non-linear in Blink (2007). Just as with the Doctor, the explanation almost immediately gets away from him. Scrooge McDuck is voiced by David Tennant, who also plays the Tenth Doctor.
In this series, Tootsie is portrayed as more savage than her original counterpart and behaves more like an actual dinosaur instead of a dog.
Webby introduces herself to Bubba as Webba, which is what he called her in the original DuckTales (1987).