When Dustin says "Never tell me the odds" before he rolls the dice is a homage to Han Solo in Star Wars: Episode V - The Empire Strikes Back (1980).
Joseph Quinn's first role as an American character. He had to learn an American accent specifically to play the role of Eddie Munson.
The song "Running Up That Hill" by Kate Bush received a resurgence in popularity following its use in this episode and later ones in this season, reaching #1 on iTunes in the U.S. on May 29, 2022, two days after the season premiered on Netflix.
While playing the Dungeons and Dragons game, Eddie Munson declares triumphantly "Vecna lives!", which is the title of the 1990 adventure module that introduced Vecna as the game's villain. (Prior to this, Vecna was only referenced in relation to two in-game items, the Hand and Eye of Vecna.)
Erica's D&D character is named Lady Applejack. Applejack is a character from My Little Pony (1986) which was revealed to be Erica's favourite television show in season 3.