Houston restored their two-run lead in the top of the fifth, as Altuve doubled and was then batted in by Brantley. Greinke left with two outs in the bottom of the fifth, having allowed one run on seven hits while striking out six batters. The Astros extended their lead to 4-1 in the top of the sixth, as Robinson Chirinos hit a home run off the left field foul pole netting. Sánchez lasted until one out in the top of the sixth, having allowed four runs on 10 hits while striking out four.
—MLB