As Dobson suggests asking the patient's dead mother what she died of, as he's leaving the room, he flips off Taub when scratching his nose.
House calls Dr. Cole "Big Love" for being a Mormon. Anne Dudek, who plays Amber, also starred the show "Big Love" when she was working on House.
Azura Skye's (the patient) & Caroline Lagerfelt's (her mother) characters died in season 7 of Buffy the Vampire Slayer. Azura Skye played Cassie Newton (a student & friend of Dawn played by Michelle Trachtenberg, who also featured as a patient of House in a previous episode). Caroline Lagerfelt played Spike's mother in a flashback.