It was a requirement by Blumhouse that the filmmakers cast gay actors for the roles of the gay characters.
In a 2019 interview with Queer Horror Movies, Carter Smith explained his broader intentions for the film: "We've spent so many years having to wade through subtextual and coded representations in genre films. There's no shortage of queer subtext - sure - but it never really felt fair to me that I didn't get to see myself in the movies I loved growing up. Midnight Kiss is a start. Hopefully one day we'll have horror films with midwestern gays and east coast gays and small town gays and we'll get the same broad representation that straight characters have enjoyed for so long. Both Erlingur Thoroddsen and I spoke at length about this in pre production. Midnight Kiss is the movie that both of us wished we had growing up."
This marks the second collaboration between Augustus Prew and Scott Evans. Both starred together in Almost Love (2019).