Due to an error in the original CBS press release, the title is listed as "Tesla + Bell + Edition + Mac" on many sites. It should have been "Tesla + Bell + Edison + Mac".
On Twitter, Co-Showrunner Terry Matalas revealed that his original pitch had been to cast Jeri Ryan as MacGyver's mother, but that he "couldn't convince the powers that be". Jeri Ryan was cast as MacGyver's aunt (and Ellen's sister) instead.
Marsha Thomason appears in NCIS: LA as another character. The two shows are part of the same universe through Hawaii 5-O.
Scottie Thompson had a recurring role on NCIS in season four and a guest appearance as a different character in season four of NCIS: Los Angeles. NCIS, NCIS: Los Angeles and MacGyver are all part of the same universe.