This episode inadvertently became the season three finale as Warner Brothers shut down the studio due to the 2019-20 COVID-19 pandemic, cutting the season short by at least one episode.
Early in the episode, Sheldon's sister is watching The Oprah Winfrey Show (1986) and her guests are The Teenage Mutant Ninja Turtles. Chuck Lorre, the producer of "The Big Bang Theory (2007)" and "Young Sheldon", wrote the theme song for the "Teenage Mutant Ninja Turtles (1987)" cartoon series.
Sheldon's video presentation of why he should go to college can be seen as a prelude to how he runs his later YouTube show, "Fun with Flags", particularly the title visible behind him, in the exact same handwriting, and how he puts up his hand to "present" the title.
Mary tells George that a school in Germany sent them a letter. In "The Big Bang Theory", Sheldon tells Penny that he spent a semester there as a visiting Professor.
The Teenage Mutant Ninja Turtles appeared on "The Oprah Winfrey Show" in the fifth season of the show, in 1990.