In the background of the lobby, a sign above the doors reads, "Carl Binder Memorial Theatre." Carl Binder is one of the writers on Stargate: Atlantis (2004).
Dr. Keller's reference to her uncle George's thoughts about "saving the planet" is most likely a nod to stand-up comedian George Carlin's skit about that very subject.
Dr. Keller asks if Rodney has 'tried these strawberries?' on the plane. Strawberries are a rare and much-treasured treat for Kaylee, Jewel Staite's Firefly (2002) character.
Bill Nye is seen talking to a man in a wheelchair who is speaking through a computer-generated voice. This character is meant to represent theoretical physicist and cosmologist Stephen Hawking.
Dave Foley (Malcolm Tunney) previously voiced Flik, an inventor whose creations frequently ended in disaster, in A Bug's Life (1998).