As West drives the fancy buggy toward town, the location at which his horse's reins are tied to the buggy changes between shots.
The amount of beans in the frying pan increases after dog swipes it.
In the gunfight scene between the characters Mr. Mitchell & Mr. Baker, you can see what appears to be clear Scotch tape/cellophane tape wrapped around the handle of Mr. Mitchell's gun.
Tracks of treaded tires - probably a camera truck - can be seen in the dust as West rides out of the ranch gate.
In the first scene with Grandma Melody and Millie, Melody is wearing hearing aids.
In 'Doc West Part 2' the character Millie Mitchell suddenly has an Italian accent where she only had an American accent in part one.