The real Ben Carson can be seen briefly as an extra walking down the hallway reading a chart and wearing the same blue scrubs as Cuba Gooding Jr..
The library that Mrs. Carson cleans at the professor's house is the library at the Biltmore in North Carolina.
Cuba Gooding Jr. (Ben Carson) and Aunjanue Ellis-Taylor (Candy Carson) are both the same age as Kimberly Elise, the actress who portrays Ben Carson's mother in the film.
Ben Carson announced in May of 2015 that he was running as a Republican for president of the United States, his first attempt for public office. However, he withdrew in early March 2016.
Cuba Gooding Jr. and Aunjanue Ellis play husband and wife in Men of Honor *2000*