This episode marks the second time one of Ash's Pokémon defeats a Legendary Pokémon. The first was in The Symbol Life (2005), with Charizard defeating Articuno. Also, both of the Legendary Pokémon beaten in these two episodes were Ice-type Pokémon that are part of a Legendary trio.
This is the final appearance of Scott.
Ash continues his rematch against Brandon and wins, earning the Brave Symbol and entering the Battle Frontier Hall of Fame.
Ash's Bulbasaur, Charizard, and Squirtle return to Professor Oak's Laboratory, the Charicific Valley, and the Squirtle Squad, respectively.
The dub episode title is a pun on the famous phrase "Space, The Final Frontier" from the sci-fi series Star Trek (1966).