Episode dated 18 March 2021
- Episode aired Mar 18, 2021
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Jonathan Ashworth
- Self - Shadow Health Secretary
- (as Jonathan Ashworth MP)
Adam Finn
- Self - Bristol Children's Vaccine Centre
- (as Professor Adam Finn)
Boris Johnson
- Self - Prime Minister of the United Kingdom
- (as Boris Johnson MP)
Pauline Paterson
- Self - Co-Director, The Vaccine Confidence Project
- (as Dr Pauline Paterson)
June Raine
- Self - CEO, Medicines & Healthcare Products Regulatory Agency
- (as Dr June Raine)
Chris Whitty
- Self - Chief Medical Officer
- (as Professor Chris Whitty)
Johnny Depp
- Self
- (archive footage)
- (uncredited)
Amber Heard
- Self
- (archive footage)
- (uncredited)
Storyline
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