Hayes warns Meredith on her trip to Minnesota saying "I hear they sculpt heads out of butter." Each year at the Minnesota state fair, candidates for the Princess Kay of the Milky Way scholarship competition have their bust carved from a 90lb block of butter.
Jesse Williams (Dr. Jackson Avery), Giacomo Gianniotti (Dr. Andrew DeLuca) and Greg Germann (Dr. Tom Koracick) are no longer part of the main cast.
The title, "Here Comes the Sun", is a song by the English rock band the Beatles from their 1969 album Abbey Road.
Chris Carmack (Dr. Atticus Lincoln) and Peter Gallagher (Dr. David Hamilton) have previously worked together on The O.C