This episode marks the final appearances of Lee Thompson Young as Cyborg and Phil Morris as the Martian Manhunter.
This is the first live-action appearance of Granny Goodness, who is is the 73rd DC Comics character adapted into the series.
Although Dinah, Victor, John, Courtney and Carter appear in the episode, they are uncredited despite the facts they're all being played by their regular actors and that they all have dialogue.
In Superman: The Movie, when Jor-El takes the young Clark on his journey through the 28 known galaxies, he says that 12 Earth years will have passed. This is when Superman is first seen in the movie, so there is significance that Clark's dream sequence at the start of the episode takes place in 2013, 12 years after Smallville first started.
This is the second season finale to feature John Jones after Season Six's finale "Phantom", although this time, he's uncredited.