While Rodger is wheeling Stan into the lab at Area 51, if you look you can see the old racist lady from season 1 episode 5 Rodger Codger. She's suspended in a tube because Stan told Bullock she was the alien.
During the scene where Roger see's his life flash before his eyes, he is seen getting drunk with the captain of a ship that's about to hit an iceberg. The ship is shown to be called El Valdez, which in 1984, caused an oil spill after hitting something in the ocean.
The title is a reference to the phrase "you bet your life"