We see a flashback of Bill Compton in London in 1982. He speaks with an English accent. Stephen Moyer - who plays Bill - is actually English. His real accent is more Received Pronunciation, though he was born in Essex, and the accent he uses in this episode is more cockney Londoner.
As Sookie is leaving Fangtasia and walking through the mob, one of the protestors can be seen wearing a "Palin 2012" T-Shirt with a red, white and blue elephant on it.
Louis Pasteur is mentioned as a scientist of the time by Nan Flanagan in the 1980s flashback, but Pasteur died in 1895. However, it is also mentioned that he is a vampire. In the books it is also mentioned as a vampire.