Devon is proud of his first clinical trial patient, nerdy physics teacher Albert Soriano. When early treatment causes a number of health problems, Albert insists upon continuing despite his wife Grace's objections. Devon struggles to follow Albert's wishes, but is ultimately able to help Albert persist the treatment with Conrad talking into Grace. Leela treats workaholic architect Mariana, whose lung keeps collapsing apparently untriggered;, eventually diagnosing endometriosis; the treatment may compromise Mariana's fertility, which she accepts. Leela later tells Devon that she isn't sure she will ever want children, unlike Devon; Leela donates eggs to twin Padma while also freezing some for her own future. Bell is frustrated with lazy bureaucracy at the state medical board and investigates a patient's complaints; finding more cases against the same surgeon, and promises to act even if the board doesn't. While treating a John Doe who has suffered a fatal drug overdose, Cade discovers he used a forged prescription with Conrad's name on it and puts him in touch with the FBI, where Cade reveals that she had worked as FBI undercover helping to take down pill mills, but mob threats became unacceptable, .forcing her is to move around so much and avoid personal relationships, as now with Conrad.
—KGF Vissers