For the pickle voices, actors gargled water as they read their lines.
The animators also added an "Easter Egg" hidden fruit, which can be seen several times in the movie. It's name is Sasquash, and is shaped like a hairy gourd.
Terry Crews replaced Mr. T as the voice of Earl Devereaux from Cloudy with a Chance of Meatballs (2009). Mr. T was asked to voice the character for the sequel, but declined. Many of Devereaux's body and facial expressions in the sequel were based on Crews' on-screen presence.
Sam Sparks' outfit when she returns to Swallow Falls is the same as Laura Dern's character in Jurassic Park (1993).
The film was originally going to be called "Cloudy 2: Revenge of the Leftovers".