Brent Antonello and Rick Gonzalez have their pictures and names added to the opening credits in this episode.
Rat-bite fever is caused by the spread of infectious bacteria from rats to humans, its main source of transmission is from bites but it can also spread via contact with infected urine and feces; other animals like gerbils, squirrels, dogs and cats can carry and transmit the disease as well. There are two types of rat-bite fever: streptobacillary which is caused by Streptobacillus moniliformis and is found in North American rats and spirillary caused by Spirillum minus and is mainly found in Africa and Asia. Symptoms of rat-bite fever depend on the type, both types cause a rash to spread around the bite. Other symptoms of strepto RBF are chills, fever, vomiting, headaches, muscle aches, joint pain and swelling, it can also cause ulcers and swelling on the hands and feet. Spirillary RBF symptoms are rather different and often involve issues with the lymph nodes, namely swelling and pain, the most common locations of lymph node swelling are in the neck, groin, and underarm. Sometimes a rash will spread across the body, which can be painful. Without treatment RBF can be fatal, especially if it progresses to the point of sepsis, before the discovery of antibiotics many cases were fatal. Even with treatment recovery can take up to a year, the antibiotic found to be most effective in treating RBF is penicillin, and erythromycin or tetracyclines are also effective for treating those with an allergy to penicillin.
This episode is likely named after the movie of the same name which stars Leonardo DiCaprio, Tom Hanks and Christopher Walken. This makes it the second of Organized Crime to be named after a DiCaprio movie, the first being I Got This Rat (2021) back in the first season, which was named after a quote from The Departed (2006).