Directors Jason Miller and Seth Savoy began making films together at the University of Central Arkansas. "Blood Brothers" was conceived as a means of continuing that partnership after Savoy moved to Chicago to attend Columbia College. Miller wrote and directed the Arkansas portion of the film, while Savoy wrote and directed the Chicago portion of the film.
Lead Actor Jeff Fuell is also the Designer of both Directors Production Company Logos and created the original animations for both seen in the Films opening Credits.
Though shot by 2 different directors with their own respective crews, there were 2 individuals involved with both shoots. Brandon Riley (cinematographer)and Kyle Wigginton (actor)
The First Day of the Arkansas Shoot was the one and only day out of both shoots that Lead Actors Jeff Fuell and Kyle Wigginton ever worked together.
Lead Actor Jeff Fuell, also an accomplished graphic designer, was responsible for designing the films official poster.