Curiously, in Russell's story, both Doug and Carley's corpse have noticeably been moved, now both facing in the direction where the RV came from. Also, the walker parted in two by Kenny, is no longer present.
In Vince's story, if you chose to shoot off Justin's foot, he's lying a foot away from Clyde, but in the overhead shot of Vince and Danny escaping, Justin is lying on him.
If you chose to leave in the RV in Shel's story, the RV accelerates too quickly to be realistic.
In the epilogue scene, before the photos are being thrown in the fire, Wyatt's picture shows he's wearing a baseball cap, but earlier in the game when displayed on the notice board, he wasn't.
In the end credits, Roberto's name is listed as "Robert".
Bonnie's image appears under "Stayed at the camp" in the end character statistics, yet she will join Tavia regardless of the choices.
In Vince's story, if you chose to shoot off Danny's foot, Vince's right hand goes through his handcuffs when you fire the first time.