A majority of this episode is a parody of The Silence of the Lambs.
Anthony Heald who played Dr Slarm played a very similar role in The Silence of the Lambs (1991) as Dr Fredrick Chilton.
Special Guest Stars: Noah Munck, Reed Alexander, Danielle Morrow and Jerry Trainor as Nora Dershlit, Gibby Gibson, Nevel Papperman and Crazy Steve.
This show had previously brought iCarly and Victorious into the same universe. The appearance of Jerry Trainor as Crazy Steve in this episode brings Drake and Josh into this universe as well.
Most of the iCarly pictures are from the series finale iGoodbye.