The short was shot at the Weldon-Glasson House built in 1880, and is owned by Paul Gresock and Christal Hayes. It is the oldest house in the Logan Heights neighborhood of San Diego, and is the site of San Diego's first petting zoo. It is listed on the San Diego Historical Landmark Registry.
The creation of the "The Case of Evil" was prompted in part by a challenge issued from Horrible Imaginings Horror Film Festival director Miguel Rodriguez to director Neal Hallford to create something truly "unique" for the festival.
The two chickens that appear briefly in the opening moments of the short are named Matilda and Hazel.
Although "The Case of Evil" is the first appearance of Rebecca Sausedo in a film, it is not her first experience as an entertainer. Before moving to the United States, she was a recording artist in Latin America.
The piano parts of the score were performed on what is billed as "The Longest Piano In the World". Built by a 16 year old kid from Timaru, New Zeland, it's 18 feet long (because that's how much room he had in his barn) which is twice the size of a standard concert grand.