The Matsuno brothers struggle to find employment. Later, Osomatsu tries to take an interest in his brothers' lives but winds up being a nuisance to them.
Todomatsu starts to work at a stylish cafe. His brothers try to disturb his fulfilling life. / Dekapan and Dayon enjoy a carefree travel together toward north.
Captain Choromatsu waits a man while he carries out a murder case investigation with Detective Todomatsu. / Totoko wants to be a popular idol, but reality is so cruel.
Karamatsu ends up as Chibita's apprentice at his oden stand. Meanwhile, Jyushimatsu falls in love and his brothers try to help him achieve his romance.
Iyami and Chibita dress up as girls, and trick the Matsuno brothers into falling in love with them. It's only a matter of time before this plan goes bad.
A salaryman named Sanematsu takes care of his six siblings, the Matsuno brothers become girls and argue, and a fight between Choromatsu and Osomatsu occurs.
The brothers all catch colds. Later, the brothers question Todomatsu about all the things he hasn't told them about his personal life. Choromatsu is a paranoid vice-principal overly worried about plans for his school's cultural festival.
Jyushimatsu goes to a job interview, proving to be a total nuisance for the interviewers. Chibita is asked out on a date by the fairy of a flower he saved.
In an apocalyptic world, the Idol Matsunos battle against Iyami and Dekapan, who are robbing the dry-skinned citizens of all of their lotion. Ichimatsu is forced to pretend to be Karamatsu after Osomatsu catches him wearing his clothes.
Wanting to become the main protagonist of the franchise again, Iyami holds a bizarre kart race to determine who the protagonist of Osomatsu-san will be.
Hatabou starts his own catering service. Later, Osomatsu and Karamatsu play as delinquent high school students competing to see who's the toughest. Afterwards, Iyami starts a comedy class hoping to earn a quick buck.
On a rainy evening, the brothers play a game of mahjong. Later, the brothers suddenly find themselves joined by a seventh brother, Godmatsu, who was allegedly born from the goodness that fell out of the brothers' hearts.
Todomatsu holds auditions to take one of his brothers with him to a mixer, struggling to find anyone worth taking. Meanwhile, Iyami meets a kung-fu master who believes him to possess a special technique.
When the family heater runs out of kerosene, the brothers to force each other to get a refill. Meanwhile, Osomatsu, Karamatsu, and Choromatsu find themselves in an underground village populated by a tribe of Dayon people.
Totoko is jealous when people start getting more success than her. Meanwhile, Choromatsu manages to land a job and moves out of the house, with the other brothers soon following suit, leaving just Osomatsu alone.