Sam Peterson, who is played by Kurtwood Smith, calls Rooster a dumbass in this episode. This is Smith's catchphrase as Red Forman in That 70's Show which he starred in with Kutcher and Masterson.
Rooster comments on Colt (Ashton Kutcher) learning things from watching Shark Tank. Ashton Kutcher had a few guest stints on Shark Tank as an investor.
Beau has a 98% blockage in the artery referred to as "The Widowmaker". This is the Left Anterior Descending artery or LAD. This location is the leading cause of Sudden Cardiac Death (SCD) due to arterial cardiac blockage.
The shot that Colt orders is called The Five Points. A tornado is something totally different with different alcohol in it.