MIT star graduate and utterly creative whiz kid Angus MacGyver joined the US top-secret Department of Secret Services (DXS), which executes ultra-covert missions. Director Patricia Thornton dispatched him, covered only by slick buddy Jack Dalton, to steal a bio-weapon of mass destruction from the Italian villa where it was to be auctioned, but at their getaway vehicle, a ruthless fiend keeps their backup teammate Nikki Carpenter -Mac's girl friend- hostage, demands the canister and kills her anyway. Months later, he returns from recovery leave to chase the same fiend, who has demonstrated in a polar station the ability to use the very bio-weapon, which may exterminate humanity. Mac and Dalton are in for an extra bitter surprise.
—KGF Vissers