- Firehouse 51 responds to the scene of a blaze that puts many lives in danger, including someone related to a Chicago police officer.
- Truck and squad are called to aid in a massive all-city response when an old, ill-equipped factory-turned live/work space quickly turns into a firestorm, trapping countless unsuspecting victims. The dire situation quickly turns personal when it is discovered that one of Chicago PD's own has a family member at the scene. With the rescued victims in need of serious medical attention, the doctors and nurses of Chicago Med are tested as the major influx of patients are brought through their doors. Meanwhile, in the aftermath, the building owner steps forward to cooperate with the ongoing investigation, but the situation takes a sudden and unexpected turn.—NBC
- When a fire breaks out in an old factory, the squad goes and finds several kids trapped inside. They get some out but there are more so they go in but Boden tells them to go out. But Detective Olinsky shows up and says his daughter is inside. Boden goes in and finds her but she's in bad shape and taken to Chicago Med where Will Halstead and Natalie Manning try to save her. After the fire is out, thy try to find out if it was an accident but that's not what they find out. Dawson and Brett help a young man find the girl he was with when the fire broke out.—rcs0411@yahoo.com
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