The song was partly recorded at Rockfield Studios in Wales.
Besides using his grand piano as usual, Mercury overdubbed the song with an upright piano to give the track a vaudeville sound.
"Killer Queen" was Queen's breakthrough hit, reaching number two in the United Kingdom and number twelve in the United States.
The song was regularly performed between 1974 and 1981 as part of a medley.
The song won Mercury his first Ivor Novello Award.