This marks the 300th episode of the series run.
The new interns hangout in the tunnels just like M.A.G.I.C used to do, and glasses trips like George did in the pilot v
The majority of the major cast members are mentioned or referenced in this episode: Christina, George, Izzy, Derek, Mark, Lexie, Callie, and Burke.
Title is a reference to a song from the musical Hamilton.
Sam wears the same blue scrubs and purple jumper, just like Izzie used to when she was a resident.