Cordellia mentions "the blood moon". In season six, the blood moon is when the ghosts in Roanoke are at their highest power.
This marks the third time that "The Murder House" has appeared in the series. The first being in season one, and then again breifly in season 5.
When Misty brings Cordelia a glass of hot tea, Cordelia asks what's in it; Misty replies "Lipton." This is a reference to a similar line in Rosemary's Baby (1968), which is also about Satanism and a coven of witches.
Dissecting something when it is still alive is called vivisection.
The shoes worn by many of the male actors in this season are designed by UK designer, Jeffery West and can be bought on their website.