The first chest compressions were performed in 1891, but the first successful chest compressions were performed by Dr George Crile (1864-1943) in 1903, about 2 years before this episode is set. Mouth-to-mouth resuscitation combined with chest compressions (CPR) was presented at a Maryland Medical Society meeting in 1960. The current recommended method of treatment is rapid chest compressions without mouth-to-mouth resuscitation.
Florence Nightingale Graham, business name Elizabeth Arden, was a Canadian-American who built an international cosmetics empire, Elizabeth Arden, Inc. She chose the forename "Elizabeth" because she had a former business partner of that name and wanted to save money on signs. She chose the surname "Arden" after a nearby farm, not after a poem (a fiction of the episode). She was instrumental in making cosmetics associated with respectable ladies rather than with prostitutes and the like.
Near the end, "Crile's chest compressions" are mentioned. Dr. George Crile (1864-1943) reported the first successful use of external chest compressions in human resuscitation in 1903. He is renown for his studies in surgical shock, and he developed nerve-block anesthesia. His son was also a surgeon, who advocated against unnecessary surgeries, especially radical mastectomies, and his grandson was a journalist for CBS.
According to this episode, Murdoch invents a robotic vacuum cleaner, essentially a Roomba. In the real world, a powered vacuum cleaner using suction was invented in 1901, about 4 years before this episode is set; the Roomba was invented in 2002.